The statement, "One of the major advantages of tablets over capsules is that a tablet is an essentially tamper-proof dosage form," suggests that tablets are less susceptible to tampering or intentional manipulation compared to capsules. Here's an explanation of why this is the case:
Solid Formulation: Tablets are solid dosage forms, which means they are made by compressing various pharmaceutical ingredients into a compact shape. This solid nature makes it challenging for someone to tamper with the contents without leaving obvious signs of interference.
Uniform Structure: Tablets are manufactured under controlled conditions, ensuring a consistent and uniform distribution of the active ingredients throughout the tablet. It is difficult for a potential tamperer to modify the contents inside without disrupting the tablet's structure.
Sealed Form: In most cases, tablets are coated with a protective film or layer, making it even more difficult for unauthorized individuals to access the inner contents of the tablet without damaging its appearance.
No Easily Removable Parts: Unlike capsules, which have two separate halves that can be opened and resealed, tablets are a single, solid unit. This lack of easily removable parts further reduces the risk of tampering.
Dissolution Rate: Tablets are designed to dissolve and release their contents in a specific manner when ingested. Tampering with a tablet might disrupt this dissolution process, making it more evident that the tablet has been interfered with.
While it is essential to recognize that no dosage form can be entirely tamper-proof, tablets offer certain advantages in this regard compared to capsules. However, it is crucial to consider the safety measures required for all medications and to store them out of reach of children or unauthorized individuals to prevent accidental or intentional tampering. Additionally, tamper-evident packaging can be employed to provide further assurance of a product's integrity.