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Grapefruit is one fruit that is not recommended for individuals with certain liver conditions or those taking specific medications. Grapefruit contains compounds that can interfere with certain enzymes in the liver, potentially affecting the metabolism of certain drugs and leading to adverse effects.

One such enzyme is CYP3A4, which is responsible for metabolizing many medications. Consuming grapefruit or grapefruit juice can inhibit this enzyme, leading to increased levels of certain drugs in the bloodstream, which could be harmful or cause unintended side effects.

If you have liver issues or are taking medications, it's crucial to consult your healthcare provider or a registered dietitian to determine which fruits are safe and suitable for your specific health condition. They can provide personalized advice on the best diet for your liver health and potential interactions with any medications you are taking.

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