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While there is ongoing research on the potential therapeutic use of ketamine for depression, it is essential to distinguish between recreational use and medically supervised treatment.

Recreational use of ketamine refers to the non-medical and illicit use of the drug for its psychoactive effects. Ketamine is a dissociative anesthetic and a controlled substance, commonly used in medical settings for anesthesia and pain management. When used recreationally, it can lead to various side effects and risks, including cognitive impairment, dissociation, hallucinations, and potential physical harm.

On the other hand, there is growing evidence supporting the use of ketamine as a treatment for depression, particularly in cases of treatment-resistant depression. Ketamine has been administered in a controlled and supervised medical setting at much lower doses than used recreationally. The treatment, known as ketamine infusion therapy, involves the intravenous (IV) administration of ketamine under medical supervision.

Studies have shown that ketamine infusion therapy can lead to rapid and significant reductions in depressive symptoms, even in individuals who have not responded well to traditional antidepressant medications. However, it's important to note that the effects of ketamine as an antidepressant are generally short-lived, and additional maintenance treatments may be necessary to sustain the benefits.

Ketamine infusion therapy is typically reserved for individuals with severe or treatment-resistant depression and is conducted by medical professionals in specialized clinics or medical settings. It is not a first-line treatment for depression, and it is not something that individuals should attempt to self-administer or use recreationally due to the potential risks and lack of supervision.

If you or someone you know is struggling with depression, it is essential to seek help from a qualified healthcare professional. They can provide a proper evaluation and recommend appropriate and evidence-based treatments tailored to the individual's specific needs.

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