King Henry VIII sought an annulment of his marriage to his first wife, Catherine of Aragon, on the grounds that it was invalid due to her previous marriage to his deceased older brother. However, the Pope refused to annul the marriage, leading King Henry to break away from the authority of the Roman Catholic Church and establish the Church of England, with himself as its Supreme Head.
King Henry VIII went on to marry five more times after his marriage to Catherine of Aragon was declared invalid by the newly established Church of England. Two of his wives, Anne Boleyn and Catherine Howard, were executed on charges of treason, and three others, Jane Seymour, Anne of Cleves, and Catherine Parr, survived him.
If the Pope had granted King Henry VIII the annulment he sought early in his reign, it is speculative to say what might have happened to his wives. Their fates would likely have been different from historical events, but it is impossible to determine with certainty how their lives would have unfolded. The political and religious landscape of England during that time was complex and influenced by numerous factors, including the decisions and actions of those in power.