The lack of a reply to a thank-you email from an interviewer is not necessarily a negative sign in and of itself. There could be various reasons why the interviewer didn't respond, and it's essential not to jump to conclusions or read too much into it.
Some possible reasons for not receiving a reply to your thank-you email could include:
Busy schedule: Interviewers often have many responsibilities, and they might not have had the time to respond to your email immediately, or they may have unintentionally overlooked it.
Company policy: Some companies have policies that discourage interviewers from engaging in post-interview communication, including responding to thank-you emails.
Decision-making process: The hiring process can take time, and the interviewer might be waiting until all interviews are completed before responding to any thank-you emails.
No action required: In some cases, the interviewer might consider your thank-you email a nice gesture but doesn't see a need to respond since the interview process has already concluded.
In any case, not receiving a response to your thank-you email should not be taken as a definite negative sign about your job application. Instead, focus on the overall impression you made during the interview and the strength of your qualifications for the position.
If it's been a while since the interview, and you haven't heard back about the job, it's generally acceptable to follow up with a brief and polite email inquiring about the status of the hiring process. This follow-up demonstrates your continued interest in the position.
Remember that job searches can be competitive, and there are many factors involved in the hiring decision. Sometimes, not getting a response to a thank-you email or not getting the job offer doesn't necessarily reflect on your qualifications or interview performance. Stay positive and keep pursuing other opportunities.