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In some cases, it is possible for ADHD medications to become less effective over time when taken consistently. This phenomenon is known as "tolerance" or "tachyphylaxis." Tolerance occurs when the body adapts to the medication, and the initial positive effects diminish or no longer produce the same level of symptom improvement.

Tolerance to ADHD medications can vary from person to person. Some individuals may experience a decrease in effectiveness after using the medication for an extended period, while others may not encounter this issue. The development of tolerance may depend on factors such as the specific medication, the dosage, individual physiology, and how the medication is used.

If you notice that your ADHD medication is becoming less effective, it's essential to discuss this with your prescribing healthcare professional. They may adjust the dosage, switch to a different medication, or suggest other treatment options to manage ADHD symptoms effectively.

Sometimes, breaks from medication or drug holidays may be recommended to help reduce tolerance and maintain the medication's effectiveness over the long term. However, any changes in medication use should always be made under the guidance and supervision of a qualified healthcare provider.

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