Please note that my knowledge is , and I do not have access to specific research papers or databases like PubMed in real-time. Consequently, I don't have access to the specific details of the paper with PMID: 30920679. Still, I can discuss some general reasons why people with anorexia or irregular eating habits might experience elevated cholesterol levels.
Starvation and metabolic changes: Anorexia nervosa is an eating disorder characterized by self-imposed starvation, which can lead to severe caloric restriction and malnutrition. In response to prolonged starvation, the body undergoes various metabolic adaptations to conserve energy. One of these adaptations is an increase in cholesterol synthesis in the liver. This can lead to elevated levels of cholesterol in the bloodstream.
Hormonal changes: Irregular eating habits, such as skipping meals or following very restrictive diets, can disrupt hormonal balance in the body. Hormones like insulin play a crucial role in regulating lipid metabolism and cholesterol levels. When eating patterns are erratic, hormonal dysregulation can occur, which might lead to elevated cholesterol levels.
Fat redistribution: In cases of severe malnutrition, the body starts breaking down its own fat stores to provide energy. This process can lead to the release of stored lipids into the bloodstream, contributing to elevated cholesterol levels.
Reduced liver function: Prolonged malnutrition and caloric restriction can negatively impact liver function. The liver plays a vital role in cholesterol metabolism, and when its function is compromised, it may lead to an accumulation of cholesterol in the blood.
Lack of essential nutrients: Anorexia and irregular eating habits can result in deficiencies of essential nutrients, such as omega-3 fatty acids. These nutrients play a role in maintaining healthy cholesterol levels, and their absence can contribute to lipid imbalances.
Stress-induced changes: Eating disorders like anorexia are often associated with high levels of stress and anxiety. Chronic stress can affect lipid metabolism and contribute to elevated cholesterol levels.
It's essential to remember that every individual's situation is unique, and multiple factors can contribute to elevated cholesterol levels in people with eating disorders. Additionally, having elevated cholesterol levels can be detrimental to overall health and can lead to various cardiovascular problems if left untreated.
If you have concerns about cholesterol levels or any health-related issues, it is crucial to seek advice and support from qualified healthcare professionals who can provide personalized assessments and recommendations based on individual circumstances.