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Yes, sertraline (Zoloft), like many other selective serotonin reuptake inhibitors (SSRIs), can potentially cause gastrointestinal side effects, including heartburn or acid reflux. While it is not a very common side effect, some individuals may experience irritation of the esophagus, leading to a burning sensation in the throat and chest.

If you are experiencing these symptoms and suspect that they might be related to your medication, it's essential to discuss it with your prescribing doctor. They can evaluate your situation, consider other possible causes, and make adjustments to your treatment plan if needed. They might recommend trying a different medication, adjusting the dosage, or offering other solutions to manage the side effects.

It's crucial not to stop taking any medication suddenly without consulting your healthcare provider, as abruptly discontinuing antidepressants can have adverse effects. Always follow your doctor's advice and communicate any concerns or side effects you experience during the course of your treatment.

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