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Bupropion is a norepinephrine-dopamine reuptake inhibitor (NDRI) and may be considered as a part of the treatment plan for bipolar depression, especially when weight gain is a concern.

Again, it's crucial to remember that every individual's response to medications can differ, and what works well for one person may not work for another. The choice of antidepressant for bipolar disorder should be made in collaboration with a psychiatrist or other mental health professional who can closely monitor the individual's progress and adjust the treatment plan as needed.

Additionally, other treatment options for bipolar disorder, such as mood stabilizers (e.g., lithium, anticonvulsants) and psychotherapy, play a significant role in managing the condition. Combining medications with therapy and lifestyle adjustments can help improve overall outcomes and reduce the risk of mood swings.

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