I can tell you that the effectiveness of generating responses or solutions depends on the context and the type of task at hand.
For humans, the best thoughts or ideas often come when they are in a relaxed and focused state of mind. This could be during moments of solitude, meditation, or leisure activities that allow the mind to wander and make unexpected connections. Additionally, some people find that their best thoughts come when they are engaged in physical activities like walking or running, as the movement can stimulate creative thinking.
Furthermore, for problem-solving and creative tasks, a well-rested mind is usually more productive. Getting enough sleep and taking breaks during intense work sessions can enhance cognitive function and lead to better ideas.
Remember, the best time for generating thoughts and ideas can vary from person to person, and it's essential to find what works best for you. Whether it's in the morning, afternoon, or evening, the key is to create an environment conducive to concentration and inspiration.