Yes, all modern humans, including our great grandparents and the first anatomically modern humans, have 46 chromosomes.
Human beings have 23 pairs of chromosomes, with one set inherited from the mother and the other from the father. Each pair consists of one chromosome from each parent, resulting in a total of 46 chromosomes.
The first anatomically modern humans (Homo sapiens) are believed to have emerged around 300,000 to 200,000 years ago in Africa. These early humans had the same 46-chromosome structure that all present-day humans have.
It's important to note that there were other human species, such as Neanderthals and Denisovans, that also lived in the past. Neanderthals, for example, had a slightly different chromosome count, with 22 pairs of chromosomes and an additional pair of sex chromosomes (X and Y), making a total of 46 chromosomes as well. However, these other human species are now extinct, and modern humans are the only surviving species of the Homo genus with 46 chromosomes.