Space Colonization: If humans establish colonies on other planets, they might experience further adaptations to those environments, such as low gravity.
It's important to reiterate that these speculations are highly uncertain and are often the subject of science fiction rather than scientific research. Additionally, the future of humanity's appearance may not solely depend on natural evolution but could be heavily influenced by our ability to manipulate our biology through technology, genetic engineering, and other means.
As of now, we cannot accurately predict the specific physical appearance of humans in 100,000 years or whether we will even look like recognizable humans at all. Evolution is a slow and complex process, and predicting its outcomes over such vast timeframes remains speculative and challenging.