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Fentanyl and heroin are both opioids, but they have different pharmacological properties and medical uses, which explain why fentanyl is used in medicine, but heroin is not.

  1. Pharmacological Differences: Fentanyl is a synthetic opioid, while heroin is derived from morphine, which is extracted from the opium poppy plant. Synthetic opioids like fentanyl can be precisely manufactured in laboratories, ensuring consistency in potency and purity. On the other hand, heroin produced from illegal sources varies widely in quality and can be contaminated with dangerous substances.

  2. Potency and Dosage: Fentanyl is much more potent than heroin. It is estimated to be 50 to 100 times more potent than morphine and approximately 50 times more potent than heroin. This extreme potency allows for smaller doses of fentanyl to achieve the same pain-relieving effects as larger doses of other opioids, making it useful for medical purposes.

  3. Medical Use: Fentanyl is primarily used in medical settings for pain management, especially in cases of severe pain, such as during surgeries or for patients with chronic pain. It is available in various forms, including patches, injections, lozenges, and nasal sprays. Due to its potency, it is carefully administered by medical professionals to prevent overdose and adverse effects.

  4. Illicit and Dangerous Nature of Heroin: Heroin is a highly addictive illegal drug that has no approved medical use in most countries, including the United States. It is associated with numerous health risks, including overdose, infectious diseases from shared needles, and long-term health problems. Because of these risks and its addictive nature, heroin is classified as a Schedule I controlled substance in the U.S., indicating it has a high potential for abuse and no accepted medical use.

In summary, fentanyl is used in medicine due to its high potency, precise dosage control, and effectiveness in managing severe pain. Heroin, on the other hand, is illegal and not approved for medical use in most countries due to its high abuse potential, significant health risks, and lack of standardized dosage control.

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