The term "despo" is likely a shortened version of the word "desperate." In colloquial language, when girls use the term "despo" to describe someone, they are usually referring to a person, typically a guy, who is acting overly eager or desperate for attention, affection, or a romantic relationship. It's often used in a negative or dismissive manner to criticize someone's behavior that comes across as desperate or needy.
It's essential to be cautious about using or interpreting such slang terms as they can sometimes be hurtful or misinterpreted. If someone uses this term to describe you, it may be worth reflecting on your behavior and communication style to ensure you are presenting yourself in a respectful and confident manner. If you feel misunderstood, consider having open and honest communication with the person to clarify their perception of you and address any concerns they might have.