It's important to understand that drug effects can vary widely from person to person, and the concept of someone going "insane" after a single use of a drug is quite uncommon.
That said, some drugs can cause severe and unpredictable reactions, including psychotic episodes, paranoia, or hallucinations, even after just one use. These reactions are not necessarily permanent or indicative of long-term mental illness, but they can be dangerous and require immediate medical attention.
One example is the use of hallucinogenic substances like LSD (lysergic acid diethylamide) or certain synthetic cannabinoids ("spice" or "K2"). These substances can cause intense alterations in perception and may lead to distressing experiences in some individuals.
Another example is the use of certain stimulants like methamphetamine or cocaine. These drugs can cause extreme agitation, paranoia, and aggressive behavior in some users.
Additionally, substances like synthetic cathinones ("bath salts") have been associated with cases of extreme agitation, hallucinations, and violent outbursts.
It's essential to remember that drug use carries inherent risks, and any use of illicit drugs or misuse of prescription medications can have serious consequences. If you or someone you know is struggling with drug-related issues, it's crucial to seek help from a medical professional or a substance abuse counselor.