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SAM-e (S-adenosylmethionine): SAM-e is a compound that occurs naturally in the body and may play a role in mood regulation. Some studies have shown potential benefits for treating depression.

5-HTP (5-hydroxytryptophan): 5-HTP is a precursor to serotonin, a neurotransmitter that affects mood. Some people use it as a supplement for depression, but its safety and efficacy are still being studied.

Remember, self-medicating or relying solely on over-the-counter supplements for depression is not recommended. Depression is a serious medical condition that requires a comprehensive approach to treatment, which may include therapy, lifestyle changes, and, in some cases, prescription medications. Always consult with a healthcare professional to determine the most appropriate treatment plan for your specific needs.

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