The opposite of wisdom is generally considered to be "foolishness" or "ignorance." Wisdom involves the ability to make sound judgments, apply knowledge, and discern what is true, just, and appropriate. On the other hand, foolishness implies a lack of good judgment, poor decision-making, and a disregard for knowledge or experience. Ignorance, on the other hand, denotes a lack of knowledge or awareness about a particular subject or situation, which can lead to unwise actions or decisions.