The primary mechanism of action for NSAIDs is through the inhibition of an enzyme called cyclooxygenase (COX), which plays a role in the production of prostaglandins. Prostaglandins are chemical messengers in the body that are involved in various processes, including pain perception, inflammation, and regulation of body temperature.
The mechanism behind this sedative effect is not fully understood and may vary from person to person, but there are a few potential reasons:
This could lead to changes in neurotransmitter activity, potentially influencing sleep-regulating pathways in the brain.
In fact, some individuals might feel more alert due to pain relief. As with any medication, it's crucial to follow the recommended dosage and consult with a healthcare professional if you have concerns about how NSAIDs might be affecting your sleep or overall health. If you experience persistent or severe drowsiness while taking NSAIDs, it's best to seek medical advice.