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Ivermectin is an antiparasitic medication commonly used to treat certain parasitic infections in both humans and animals. While ivermectin has been shown to be generally safe and effective for its approved uses, it is contraindicated in pregnancy, especially during the first trimester. Contraindication means that the use of a particular medication is not recommended or should be avoided under certain circumstances, in this case, during pregnancy.

The primary reason ivermectin is contraindicated in pregnancy is due to limited data on its safety during this period. Conducting clinical trials on pregnant women is ethically challenging, so most medications, including ivermectin, have limited data on their potential risks and benefits during pregnancy. As a result, regulatory agencies and healthcare professionals take a cautious approach and recommend avoiding medications whenever possible, especially during the critical stages of fetal development.

Additionally, animal studies have shown some evidence of potential harm to the developing fetus when exposed to high doses of ivermectin. Though animal studies may not directly translate to human effects, they provide a basis for concern and reinforce the importance of avoiding unnecessary risks during pregnancy.

Instead of using ivermectin, pregnant women with parasitic infections should consult their healthcare provider for alternative treatments that are considered safe during pregnancy. In such cases, the healthcare provider will carefully weigh the potential risks and benefits of any medication before recommending treatment.

It is crucial for pregnant women or those planning to become pregnant to discuss any medications they are taking or considering taking with their healthcare provider. This helps ensure the health and safety of both the mother and the developing fetus throughout the pregnancy.

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