Yes, it is possible for someone to experience a major depressive episode even if they have never had a mood disorder before. In fact, this is one of the key features of major depressive disorder (MDD) - the occurrence of one or more major depressive episodes.
Major depressive disorder is a mental health condition characterized by persistent feelings of sadness, loss of interest or pleasure in activities, changes in sleep and appetite, fatigue, difficulty concentrating, feelings of worthlessness or guilt, and sometimes thoughts of death or suicide. These symptoms must be present for at least two weeks and significantly impair the individual's ability to function in daily life.
A major depressive episode can occur in individuals who have never experienced depression before and have no history of mood disorders. There can be various triggers for the onset of a major depressive episode, such as significant life stressors, trauma, loss, genetic predisposition, or even certain medical conditions. The exact cause of depression can vary from person to person, and it's often a combination of biological, psychological, and environmental factors.
If someone experiences a major depressive episode, it's essential for them to seek professional help from a mental health provider. Depression is a treatable condition, and various therapeutic approaches, including psychotherapy and medication, can be effective in managing and alleviating symptoms.